Napsin A (RBT-NAPSA), RMab

Antibodies are temperature sensitive, and MUST ship Priority Overnight!

Summary and Explanation

The activation peptides of aspartic proteinases play a role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional glycosylated aspartic proteinase precursor containg an RGD motif and an addition 18 residues at its C-terminus. In normal tissue, Napsin A antibody labels type II pneumocytes in adult lung and epithelial cells in kidney tissues. In abnormal tissues, Napsin A is a useful marker for lung adenocarcinoma.

Presentation Description

Napsin A is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Type	RMab
Clone	RBT-NAPSA
Isotype	IgG
Reactivity	Paraffin, Frozen
Application
Control