Cytokeratin 5 & 6 (RM341), RMab
SKU: Cytokeratin 5 & 6 (RM341) -RMab
Antibodies are temperature sensitive, and MUST ship Priority Overnight!
Summary and Explanation
Cytokeratin 5 (58 kDa) is a high-molecular weight, basic type of cytokeratin expressed in basal, intermediate and superficial-cell layers of stratified epithelia as well as transitional epithelia, complex epithelia, mesothelial cells and Mesothelioma. Cytokeratin 6 (56 kD) is also a high-molecular weight, basic type cytokeratin expressed by proliferating squamous epithelium often paired with Cytokeratin 16. Cytokeratin 5 & 6 antibody is positively seen in nearly 100% of Malignant Mesotheliomas and are rarely seen in Lung Adenocarcinomas. CK 5 and 6 can positively be seen in undifferentiated Large-cell Carcinoma as well as Squamous Carcinoma. Fewer than 10% of Carcinomas of the breast, colon, and prostate stain positively for this marker. Cytokeratin 5 & 6 antibody has also been used successfully as a myoepithelial cell marker in the prostate to determine malignancy.Presentation Description
Cytokeratin 5 & 6 is a rabbit monoclonal antibody for immunohistochemistry derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.Type | RMab |
---|---|
Clone | RM341 |
Isotype | IgG |
Reactivity | Paraffin, Frozen |
Application | |
Control |
Applicable Placards and Hazard Symbols
Hover over each placard to see a description of its meaning
Use the links to download available SDS, IFU or Flyer Documents
Note: please try the mirror link if you receive an errorDownload SDS | Mirror Link |
Download IFU | Mirror Link |